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Steelers0525
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"SuperBugs"

Postby Steelers0525 » Tue Feb 28, 2017 7:14 pm

The term "SuperBugs" has been thrown around recently in the past couple of years. This is not referring to insects that are going to take over the world or anything, but about diseases and how they are also adapting to humans and their ways of protecting them selves.

As you may know, bacteria and viruses have becoming stronger, and the drugs that humans have created have become weaker and weaker. This is because these diseases are adapting to us killing them in this way, just like any other organism would. This threat is not just localized either, In a study that I was reading upon, it said something along the lines of: "The bacteria that caused TB 60 or 70 years ago that would kill people left and right, is now thousands of times more resistant and less susceptible to outside sources." A lot of people have been saying that our immune system has been becoming weaker and weaker, however this is not true, it probably is getting stronger as generations pass, however since these bugs are getting stronger faster then our systems can, it just appears that way.

Now NSG what are your opinions on all of this. Do you agree with this, or think it just garbage? Do you have any suggestions on how to solve this ever growing problems?

*Siting articles is encouraged however not mandatory, it helps back your opinion, and gives others more info to create a stronger/less biased opinion*
**The word stronger can be interchangeably used with more resistance**
Last edited by Steelers0525 on Tue Feb 28, 2017 7:22 pm, edited 3 times in total.
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Uxupox
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Postby Uxupox » Tue Feb 28, 2017 7:20 pm

It's not that bacteria are becoming stronger it's that they are becoming more tolerant to the unnecessary rampage use of antibiotics.
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Postby Thermodolia » Tue Feb 28, 2017 7:21 pm

Uxupox wrote:It's not that bacteria are becoming stronger it's that they are becoming more tolerant to the unnecessary rampage use of antibiotics.

Which is why I rarely use antibiotics unless I absolutely have to.
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Steelers0525
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Postby Steelers0525 » Tue Feb 28, 2017 7:22 pm

Uxupox wrote:It's not that bacteria are becoming stronger it's that they are becoming more tolerant to the unnecessary rampage use of antibiotics.


Realized my mistake op was updated
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Steelers0525
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Postby Steelers0525 » Tue Feb 28, 2017 7:23 pm

Thermodolia wrote:
Uxupox wrote:It's not that bacteria are becoming stronger it's that they are becoming more tolerant to the unnecessary rampage use of antibiotics.

Which is why I rarely use antibiotics unless I absolutely have to.


The issue is that often doctors prescribe antibiotics that are not necessarily needed, however help. but this over a long period of time create big problems
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Uxupox
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Postby Uxupox » Tue Feb 28, 2017 7:25 pm

Steelers0525 wrote:
Thermodolia wrote:Which is why I rarely use antibiotics unless I absolutely have to.


The issue is that often doctors prescribe antibiotics that are not necessarily needed, however help. but this over a long period of time create big problems


No no it's not that. It's people that don't use it as it's prescribed.
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Steelers0525
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Postby Steelers0525 » Tue Feb 28, 2017 7:27 pm

Uxupox wrote:
Steelers0525 wrote:
The issue is that often doctors prescribe antibiotics that are not necessarily needed, however help. but this over a long period of time create big problems


No no it's not that. It's people that don't use it as it's prescribed.


Both happen more then most think, it was alot more common in the 80s , 90s and 2000s however people are realizing the dangers, however it caused a lot of 'damage'
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Uxupox
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Postby Uxupox » Tue Feb 28, 2017 7:29 pm

Steelers0525 wrote:
Uxupox wrote:
No no it's not that. It's people that don't use it as it's prescribed.


Both happen more then most think, it was alot more common in the 80s , 90s and 2000s however people are realizing the dangers, however it caused a lot of 'damage'


People are not realizing the danger. In fact I'd wager they don't care.
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I-13
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Postby I-13 » Tue Feb 28, 2017 7:43 pm

The next plague is going to be. . . interesting.

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Postby Ventaion » Tue Feb 28, 2017 7:45 pm

Conscentia wrote:


Top quality shitpost.
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Conscentia
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Postby Conscentia » Tue Feb 28, 2017 8:00 pm

Seriously though, it's a major threat to public health. Having our only means of staving off antibiotic resistance being only to control antibiotic use is very concerning. Although it prolongs the life of antibiotics, it's not a guarantee against antibiotic resistance emerging in a bacterial population and it can't help once resistance has already developed and spread through in a population. It'd be preferable if potential alternatives to antibiotics like phage therapy could be developed into a viable replacements so we're not so dependent, but as far as I'm aware it's not yet clear whether that's even viable. Developing combination treatments involving drugs aimed at first knocking out resistance is another possibility, although this might just buy time until the pathogens evolves a way around it. A third possibility could be to take an immunotherapy approach - use drugs to enhance the immune response, rather than using drugs to directly kill the pathogen.
Last edited by Conscentia on Tue Feb 28, 2017 8:04 pm, edited 1 time in total.

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Postby Neanderthaland » Tue Feb 28, 2017 8:41 pm

Uxupox wrote:
Steelers0525 wrote:
The issue is that often doctors prescribe antibiotics that are not necessarily needed, however help. but this over a long period of time create big problems


No no it's not that. It's people that don't use it as it's prescribed.

These are both serious issues, though both pale in comparison to the practice of putting antibiotics in feed for livestock.
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Postby Internationalist Bastard » Tue Feb 28, 2017 8:42 pm

Whivh is why I reky heavily on Vitamin C for my immunity
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-Ebola-
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Postby -Ebola- » Wed Mar 01, 2017 12:00 am

Obviously, the solution is to stop committing genocide against viruses and bacteria every time you get offended by our culture. It's not just antibiotics, either. You guys really need to stop with those antibacterial cleaning products. There is no reason to kill all the bacteria on your counter top just because there are a few bacteria who cause problems. You can't blame them for fighting back if you go around killing billions of them for no reason. You can use water and a traditional detergent without the antibacterial chemicals if you need to clean your counter.
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Lady Scylla
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Postby Lady Scylla » Wed Mar 01, 2017 12:11 am

Steelers0525 wrote:The term "SuperBugs" has been thrown around recently in the past couple of years. This is not referring to insects that are going to take over the world or anything, but about diseases and how they are also adapting to humans and their ways of protecting them selves.

As you may know, bacteria and viruses have becoming stronger, and the drugs that humans have created have become weaker and weaker. This is because these diseases are adapting to us killing them in this way, just like any other organism would. This threat is not just localized either, In a study that I was reading upon, it said something along the lines of: "The bacteria that caused TB 60 or 70 years ago that would kill people left and right, is now thousands of times more resistant and less susceptible to outside sources." A lot of people have been saying that our immune system has been becoming weaker and weaker, however this is not true, it probably is getting stronger as generations pass, however since these bugs are getting stronger faster then our systems can, it just appears that way.

Now NSG what are your opinions on all of this. Do you agree with this, or think it just garbage? Do you have any suggestions on how to solve this ever growing problems?

*Siting articles is encouraged however not mandatory, it helps back your opinion, and gives others more info to create a stronger/less biased opinion*
**The word stronger can be interchangeably used with more resistance**


I agree with it. It's just medical fact that they're becoming resistant. Hell, I got sick with staph that threatened to make me never walk again (or worse) and was put on antibiotics not only for it, but to deal with MRSA as a just in case measure.

http://www.bbc.com/news/health-39104411

Here's a list from WHO over the most concerning 'superbugs'.

http://www.medscape.com/viewarticle/863896

A strain of E. Coli has been found to be resistant to our last-resort antibiotics. Making it practically untreatable.

And what's more concerning is that it has developed 'Horizontal Gene Transfer'

https://www.sciencedaily.com/releases/2 ... 105900.htm

http://aac.asm.org/content/48/10/3996.full

https://www.sciencenews.org/article/bac ... appears-us

https://en.wikipedia.org/wiki/Horizontal_gene_transfer

This means that, unlike before where E. Coli could have passed genes on solely through splitting and creating children -- it can now pass on this immunity to other E. Coli or other diseases neighbouring it.

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Frank Zipper
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Postby Frank Zipper » Wed Mar 01, 2017 1:52 am

Something puzzles me about antibiotics becoming less effective through overuse. Penicillin is still used a lot, I eat blue cheese most days which contains penicillin, and yet penicillin is still effective for some things. Presumably something more complex is going on.
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Uxupox
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Postby Uxupox » Wed Mar 01, 2017 2:25 am

Lady Scylla wrote:
Steelers0525 wrote:The term "SuperBugs" has been thrown around recently in the past couple of years. This is not referring to insects that are going to take over the world or anything, but about diseases and how they are also adapting to humans and their ways of protecting them selves.

As you may know, bacteria and viruses have becoming stronger, and the drugs that humans have created have become weaker and weaker. This is because these diseases are adapting to us killing them in this way, just like any other organism would. This threat is not just localized either, In a study that I was reading upon, it said something along the lines of: "The bacteria that caused TB 60 or 70 years ago that would kill people left and right, is now thousands of times more resistant and less susceptible to outside sources." A lot of people have been saying that our immune system has been becoming weaker and weaker, however this is not true, it probably is getting stronger as generations pass, however since these bugs are getting stronger faster then our systems can, it just appears that way.

Now NSG what are your opinions on all of this. Do you agree with this, or think it just garbage? Do you have any suggestions on how to solve this ever growing problems?

*Siting articles is encouraged however not mandatory, it helps back your opinion, and gives others more info to create a stronger/less biased opinion*
**The word stronger can be interchangeably used with more resistance**


I agree with it. It's just medical fact that they're becoming resistant. Hell, I got sick with staph that threatened to make me never walk again (or worse) and was put on antibiotics not only for it, but to deal with MRSA as a just in case measure.

http://www.bbc.com/news/health-39104411

Here's a list from WHO over the most concerning 'superbugs'.

http://www.medscape.com/viewarticle/863896

A strain of E. Coli has been found to be resistant to our last-resort antibiotics. Making it practically untreatable.

And what's more concerning is that it has developed 'Horizontal Gene Transfer'

https://www.sciencedaily.com/releases/2 ... 105900.htm

http://aac.asm.org/content/48/10/3996.full

https://www.sciencenews.org/article/bac ... appears-us

https://en.wikipedia.org/wiki/Horizontal_gene_transfer

This means that, unlike before where E. Coli could have passed genes on solely through splitting and creating children -- it can now pass on this immunity to other E. Coli or other diseases neighbouring it.


Escherichia coli O104 while it's very resistant it's not untreatable.
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Postby USS Monitor » Wed Mar 01, 2017 2:27 am

Frank Zipper wrote:Something puzzles me about antibiotics becoming less effective through overuse. Penicillin is still used a lot, I eat blue cheese most days which contains penicillin, and yet penicillin is still effective for some things. Presumably something more complex is going on.


Not every infection is one of the resistant strains. There are lots of places that older varieties of bacteria can survive. For example, since wild animals aren't treated with antibiotics, they can still carry bacteria that aren't antibiotic-resistant.
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The New Telengana Rajj
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Postby The New Telengana Rajj » Wed Mar 01, 2017 2:27 am

Its Trump's fault...idk how but it is.






































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Frank Zipper
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Postby Frank Zipper » Wed Mar 01, 2017 2:32 am

USS Monitor wrote:
Frank Zipper wrote:Something puzzles me about antibiotics becoming less effective through overuse. Penicillin is still used a lot, I eat blue cheese most days which contains penicillin, and yet penicillin is still effective for some things. Presumably something more complex is going on.


Not every infection is one of the resistant strains. There are lots of places that older varieties of bacteria can survive. For example, since wild animals aren't treated with antibiotics, they can still carry bacteria that aren't antibiotic-resistant.


Ah. I think penicillin is still used for Lyme disease - which would be ticks on wild animals - that makes sense. Thank you.
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Postby Forsher » Wed Mar 01, 2017 2:41 am

They're extremely scary and I try to avoid thinking about it. There's not really anything I can do except the perverse situation of encouraging patients to complete antibiotic regimens and discouraging doctors from prescribing them.

Of course, one could try and invest money in antibiotics but the R&D for such is not worth it... and, no, longer patents wouldn't solve that issue. This is, I understand it, a popular answer for why antibiotic resistance is a growing (or, even, mature) issue... I guess you can also believe we've maxed out and must now simply accept our fate... i.e. how we used to live prior to WWII, but with internet!
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Lady Scylla
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Postby Lady Scylla » Wed Mar 01, 2017 2:58 am

Frank Zipper wrote:
USS Monitor wrote:
Not every infection is one of the resistant strains. There are lots of places that older varieties of bacteria can survive. For example, since wild animals aren't treated with antibiotics, they can still carry bacteria that aren't antibiotic-resistant.


Ah. I think penicillin is still used for Lyme disease - which would be ticks on wild animals - that makes sense. Thank you.


Here's to hoping I never get Lyme's since I'm horrendously allergic to penicillin. :lol2:

Then again. Maybe that means I'm just not antibiotic resistant and therefore I must be careful if I'm going to infect you.
Last edited by Lady Scylla on Wed Mar 01, 2017 2:58 am, edited 1 time in total.

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Postby Lautrec- » Wed Mar 01, 2017 3:47 am

This is a real and a huge problem but I can't see how it could be solved.

We live in a world where nations and organizations try to solve problems after they occur instead of preventing them beforehand. We see that with climate change, which is also a problem that can potentially destroy the global economy, yet nations barely do anything to stop it. People aren't reliable, either. Especially when there are groups that reject science and don't believe in vaccine effectiveness or climate change etc.

Nobody is going to do anything until it's too late. There will be measures only after people start dying during surgery or after visiting the hospital for an unrelated reason.
Last edited by Lautrec- on Wed Mar 01, 2017 3:48 am, edited 1 time in total.
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Postby USS Monitor » Wed Mar 01, 2017 3:55 am

Lautrec- wrote:There will be measures only after people start dying during surgery or after visiting the hospital for an unrelated reason.


Some people already have died.
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