Each individual NS poster exists in an alternate universe of Earth. In each Earth there are seven Endless with absolute powers over their respective domains.
The Endless are essentially gods that personify eternal aspects of humanity and existence.
Every version of Earth has 1 NS poster acting as one of the Endless. A poster may travel to another version of Earth but if they do so, their powers become close to non-existent until/unless they travel back to their own domain. Every domain has one of the following:
Destiny - Has absolute and complete Knowledge of everything (big and small) that will, can, and shall happen in the universe. Some things are set in stone, other things may change for that is the nature of reality. Understands more than any other entity how their own actions are constrained by the mechanisms of fate.
Death - Has complete dominion over the birth and death of all mortals. Can end the lives of anyone on the planet instantaneously. When the universe ends, will end everyone including the other Endless and themselves. On most days, runs and administers a relatively consistent statistical system where people are born and die in large numbers. Appears selectively to those who are dying. If Death attempts to kill the other Endless before the right time, they will be re-constituted because it is not the right time.
Dream - Controls the dreams and nightmares of all mortals. Can influence people's hopes, wishes, dreams and perceptions of reality/fantasy. Can put people into eternal sleep.
Destruction - Can destroy things in the mortal plane on a massive scale.
Desire - Influences people's desires and wants, especially in terms of lust and attraction but also in terms of material, career, and artistic ambition.
Despair - Influences the despair of mortals. Has the power to cause massive amounts of depression across space and time.
Delight and Delirium - Just wants to have a good time. Focuses on the pleasures, joys, and highs of life. Can help other mortals experience these things.
If some of these powers sound like they overlap, it's because they probably do. However, somehow in each and every individual universe, the seven Endless can co-exist and the universe can continue to run. Everyone is on at least some level bound by the forces of fate and so unclear rules restrict what every Endless can actually do (rules that only Destiny knows). As a result, some measure of restraint is typically employed to keep the machinery running.
Based on your IRL personality, strengths/weaknesses, interests etc... which Endless are you? In your iteration of Earth, how do you use your powers?