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Coronavirus Thread VI: Are We Nearly There Yet? (READ OP)

For discussion and debate about anything. (Not a roleplay related forum; out-of-character commentary only.)

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Should your country require everyone who can receive a COVID-19 vaccine to actually receive it?

YES
159
53%
YES, BUT there should also be exceptions for philosophical and religious reasons
20
7%
NO, BUT EMPLOYERS SHOULD DO SO THEMSELVES
15
5%
NO, BUT people should be incentivised towards taking, and/or away from not taking, a COVID-19 vaccine (perhaps through lotteries, vaccine passports, etc.)
41
14%
NO
67
22%
 
Total votes : 302

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Neutraligon
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Founded: Oct 01, 2011
New York Times Democracy

Postby Neutraligon » Tue Jun 01, 2021 8:12 pm

Kowani wrote:
Samudera Darussalam wrote:Huh, that's the first time I'm reading something like this.
Now I'm wondering what kind of rewards govt. officials will give to entice peoppe to vaccinate. A new house? An apartment suite in Manhattan? Wyoming?

so far: money prizes in Cali, New Mexico, and Ohio, gift cards pretty much everywhere, beers in New Jersey, and amusement park tickets in Illinois, scholarships in quite a few states, and now guns in WV
there's probably some other stuff i missed, but meh

Oregon has had a number of prizes from preseason tickets to money.
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Kowani
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Postby Kowani » Tue Jun 01, 2021 10:36 pm

The Pharmaceutical Industry launches ad campaign against Biden over vaccine waivers

The lobbying group that represents several top pharmaceutical companies last month quietly launched a campaign against President Joe Biden and his decision to back waiving intellectual property protections for Covid-19 vaccines.

The Pharmaceutical Research and Manufacturers of America, known as PhRMA, is a political advocacy group that represents more than 30 pharmaceutical firms, including Covid vaccine makers Pfizer and Johnson & Johnson. Late last month it started running a digital ad campaign on Facebook and Google targeting Biden’s decision, a CNBC search of the companies’ ad archives revealed.

While PhRMA blasted the Biden administration’s move shortly after the announcement, the group didn’t officially announce a campaign against the waiver push. The details of the effort had yet to be reported.

Proponents of waiving patent protections say it allows poorer nations to ramp up production of the Covid vaccine.

After publication of this story, a PhRMA spokesperson released this statement to CNBC:

“Biopharmaceutical research companies are committed to achieving equitable access around the world to COVID-19 vaccines, and that is why we’re educating policymakers and the public about our ongoing efforts to increase vaccine supply for global demand, the risks of waiving intellectual property protections, and the need to address the real issues driving vaccine inequity.”

PhRMA’s ads on Google call out Biden by name.

“Biden’s Harmful Vaccine Stance,” reads one of the Google ads reviewed by CNBC. “Biden’s Damaging IP Stance,” reads another Google spot.

Google’s ad archive shows that one of the ads on the search platform cost the group between $1,000 and $50,000. The other cost under $100. Both targeted the area in and around Washington, D.C., according to Google’s data.

Each Google ad was live for up to five days through the end of May, according to the search engine’s ad transparency report.

The Google ads link to articles written by PhRMA’s public affairs team and published on the group’s website. One of the posts bears the headline: “The Biden Administration allows politics to upend a pragmatic pandemic response.” The article claims that “not only will this policy do nothing to help save lives globally, it could have a damaging impact for American patients.”

Another PhRMA post cites a Hill-HarrisX poll that shows that 57% of registered voters who took the survey are against the waiver.

Facebook’s ad library shows that PhRMA spent over $245,000 since late April and throughout May on digital spots. A fraction of that spending went toward ads that ran at the end of May taking aim at Biden’s decision.

The Facebook ads all had the same message: “Eliminating IP protections undermines our global response to the pandemic and compromises safety.” One spot had a potential reach of up to 1 million people, according to data from the social media giant. That ad targeted people in Maryland, Washington, D.C., and Virginia. The PhRMA Facebook ads are currently inactive.

Even prior to launching the digital ad campaign, PhRMA was actively lobbying the Biden White House on the patent waiver issue.

First-quarter lobbying disclosure reports, which span from the month Biden was inaugurated through March, show that PhRMA lobbied the Executive Office of the President as well as the Department of Health and Human Services on “international intellectual property and market access policy issues,” among other concerns.

PhRMA spent just over $8.5 million on lobbying over the course of the first three months of 2021. Data from the nonpartisan Center for Responsive Politics shows the organization spent over $25 million in 2020 and nearly $30 million in 2019 on lobbying-related expenditures.
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Neutraligon
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New York Times Democracy

Postby Neutraligon » Tue Jun 01, 2021 10:41 pm

Kowani wrote:The Pharmaceutical Industry launches ad campaign against Biden over vaccine waivers

The lobbying group that represents several top pharmaceutical companies last month quietly launched a campaign against President Joe Biden and his decision to back waiving intellectual property protections for Covid-19 vaccines.

The Pharmaceutical Research and Manufacturers of America, known as PhRMA, is a political advocacy group that represents more than 30 pharmaceutical firms, including Covid vaccine makers Pfizer and Johnson & Johnson. Late last month it started running a digital ad campaign on Facebook and Google targeting Biden’s decision, a CNBC search of the companies’ ad archives revealed.

While PhRMA blasted the Biden administration’s move shortly after the announcement, the group didn’t officially announce a campaign against the waiver push. The details of the effort had yet to be reported.

Proponents of waiving patent protections say it allows poorer nations to ramp up production of the Covid vaccine.

After publication of this story, a PhRMA spokesperson released this statement to CNBC:

“Biopharmaceutical research companies are committed to achieving equitable access around the world to COVID-19 vaccines, and that is why we’re educating policymakers and the public about our ongoing efforts to increase vaccine supply for global demand, the risks of waiving intellectual property protections, and the need to address the real issues driving vaccine inequity.”

PhRMA’s ads on Google call out Biden by name.

“Biden’s Harmful Vaccine Stance,” reads one of the Google ads reviewed by CNBC. “Biden’s Damaging IP Stance,” reads another Google spot.

Google’s ad archive shows that one of the ads on the search platform cost the group between $1,000 and $50,000. The other cost under $100. Both targeted the area in and around Washington, D.C., according to Google’s data.

Each Google ad was live for up to five days through the end of May, according to the search engine’s ad transparency report.

The Google ads link to articles written by PhRMA’s public affairs team and published on the group’s website. One of the posts bears the headline: “The Biden Administration allows politics to upend a pragmatic pandemic response.” The article claims that “not only will this policy do nothing to help save lives globally, it could have a damaging impact for American patients.”

Another PhRMA post cites a Hill-HarrisX poll that shows that 57% of registered voters who took the survey are against the waiver.

Facebook’s ad library shows that PhRMA spent over $245,000 since late April and throughout May on digital spots. A fraction of that spending went toward ads that ran at the end of May taking aim at Biden’s decision.

The Facebook ads all had the same message: “Eliminating IP protections undermines our global response to the pandemic and compromises safety.” One spot had a potential reach of up to 1 million people, according to data from the social media giant. That ad targeted people in Maryland, Washington, D.C., and Virginia. The PhRMA Facebook ads are currently inactive.

Even prior to launching the digital ad campaign, PhRMA was actively lobbying the Biden White House on the patent waiver issue.

First-quarter lobbying disclosure reports, which span from the month Biden was inaugurated through March, show that PhRMA lobbied the Executive Office of the President as well as the Department of Health and Human Services on “international intellectual property and market access policy issues,” among other concerns.

PhRMA spent just over $8.5 million on lobbying over the course of the first three months of 2021. Data from the nonpartisan Center for Responsive Politics shows the organization spent over $25 million in 2020 and nearly $30 million in 2019 on lobbying-related expenditures.


Those vaccines that had government aid should have the waiver.
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CoraSpia
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Ex-Nation

Postby CoraSpia » Wed Jun 02, 2021 12:26 am

Vetalia wrote:
Borderlands of Rojava wrote:Vetalia, why? You're really gonna post your vaccine card to prove a point on a random site?


I don't like being called a liar regarding something as important as a COVID vaccination and needed to set the record straight. I also believe it is important to differentiate the lockdown-skeptics from the goofy, extreme types that latch on to our valid criticisms regarding the pandemic response with their conspiracy theories and anti-vax nonsense.

These safe, effective vaccines have and will continue to save countless lives and will play a critical role in ending this pandemic. All of the key information has been carefully redacted to prevent some idiot from abusing it to make a fake vaccination card, of course.

You can already buy fake vaccination cards in the UK. Kind of fucks up vaccine passports as an idea.
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CoraSpia
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Ex-Nation

Postby CoraSpia » Wed Jun 02, 2021 12:28 am

Neutraligon wrote:
Kowani wrote:The Pharmaceutical Industry launches ad campaign against Biden over vaccine waivers

The lobbying group that represents several top pharmaceutical companies last month quietly launched a campaign against President Joe Biden and his decision to back waiving intellectual property protections for Covid-19 vaccines.

The Pharmaceutical Research and Manufacturers of America, known as PhRMA, is a political advocacy group that represents more than 30 pharmaceutical firms, including Covid vaccine makers Pfizer and Johnson & Johnson. Late last month it started running a digital ad campaign on Facebook and Google targeting Biden’s decision, a CNBC search of the companies’ ad archives revealed.

While PhRMA blasted the Biden administration’s move shortly after the announcement, the group didn’t officially announce a campaign against the waiver push. The details of the effort had yet to be reported.

Proponents of waiving patent protections say it allows poorer nations to ramp up production of the Covid vaccine.

After publication of this story, a PhRMA spokesperson released this statement to CNBC:

“Biopharmaceutical research companies are committed to achieving equitable access around the world to COVID-19 vaccines, and that is why we’re educating policymakers and the public about our ongoing efforts to increase vaccine supply for global demand, the risks of waiving intellectual property protections, and the need to address the real issues driving vaccine inequity.”

PhRMA’s ads on Google call out Biden by name.

“Biden’s Harmful Vaccine Stance,” reads one of the Google ads reviewed by CNBC. “Biden’s Damaging IP Stance,” reads another Google spot.

Google’s ad archive shows that one of the ads on the search platform cost the group between $1,000 and $50,000. The other cost under $100. Both targeted the area in and around Washington, D.C., according to Google’s data.

Each Google ad was live for up to five days through the end of May, according to the search engine’s ad transparency report.

The Google ads link to articles written by PhRMA’s public affairs team and published on the group’s website. One of the posts bears the headline: “The Biden Administration allows politics to upend a pragmatic pandemic response.” The article claims that “not only will this policy do nothing to help save lives globally, it could have a damaging impact for American patients.”

Another PhRMA post cites a Hill-HarrisX poll that shows that 57% of registered voters who took the survey are against the waiver.

Facebook’s ad library shows that PhRMA spent over $245,000 since late April and throughout May on digital spots. A fraction of that spending went toward ads that ran at the end of May taking aim at Biden’s decision.

The Facebook ads all had the same message: “Eliminating IP protections undermines our global response to the pandemic and compromises safety.” One spot had a potential reach of up to 1 million people, according to data from the social media giant. That ad targeted people in Maryland, Washington, D.C., and Virginia. The PhRMA Facebook ads are currently inactive.

Even prior to launching the digital ad campaign, PhRMA was actively lobbying the Biden White House on the patent waiver issue.

First-quarter lobbying disclosure reports, which span from the month Biden was inaugurated through March, show that PhRMA lobbied the Executive Office of the President as well as the Department of Health and Human Services on “international intellectual property and market access policy issues,” among other concerns.

PhRMA spent just over $8.5 million on lobbying over the course of the first three months of 2021. Data from the nonpartisan Center for Responsive Politics shows the organization spent over $25 million in 2020 and nearly $30 million in 2019 on lobbying-related expenditures.


Those vaccines that had government aid should have the waiver.


When the aid was being given, was a patent waiver laid out in the contract with the companies as a condition of accepting it?
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Austria-Bohemia-Hungary
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Postby Austria-Bohemia-Hungary » Wed Jun 02, 2021 12:52 am

CoraSpia wrote:You can already buy fake vaccination cards in the UK.

Do these people really want to go back to an age where we locked up plague victims on previously unpopulated Venetian islands for a whole month just to be sure?
Last edited by Austria-Bohemia-Hungary on Wed Jun 02, 2021 12:54 am, edited 1 time in total.
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CoraSpia
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Postby CoraSpia » Wed Jun 02, 2021 1:06 am

Austria-Bohemia-Hungary wrote:
CoraSpia wrote:You can already buy fake vaccination cards in the UK.

Do these people really want to go back to an age where we locked up plague victims on previously unpopulated Venetian islands for a whole month just to be sure?

I think they want to go on holiday and don't want to have to get a vaccine to live their lives. Government coercion being bad was something we used to remember before last year.
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Austria-Bohemia-Hungary
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Postby Austria-Bohemia-Hungary » Wed Jun 02, 2021 1:09 am

CoraSpia wrote:
Austria-Bohemia-Hungary wrote:Do these people really want to go back to an age where we locked up plague victims on previously unpopulated Venetian islands for a whole month just to be sure?

I think they want to go on holiday and don't want to have to get a vaccine to live their lives. Government coercion being bad was something we used to remember before last year.

So fuck the rest of you all got mine. I start to see why PRC, accursed place it may be turned apt complexes into literal prisons when shit became too hard to cover up.
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The Free Joy State
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Postby The Free Joy State » Wed Jun 02, 2021 1:10 am

Austria-Bohemia-Hungary wrote:
CoraSpia wrote:You can already buy fake vaccination cards in the UK.

Do these people really want to go back to an age where we locked up plague victims on previously unpopulated Venetian islands for a whole month just to be sure?

Whatever the "market" -- no matter what harm it may do -- there is someone, somewhere who (whether for cold, hard money, or some other poor reason) is willing to supply it.

Fortunately, easily-forgeable vaccination cards are not considered proof of vaccination for a holiday. Only a governmentally-dispensed certificate or the app is.
Last edited by The Free Joy State on Wed Jun 02, 2021 1:15 am, edited 3 times in total.
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Austria-Bohemia-Hungary
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Postby Austria-Bohemia-Hungary » Wed Jun 02, 2021 1:12 am

The Free Joy State wrote:
Austria-Bohemia-Hungary wrote:Do these people really want to go back to an age where we locked up plague victims on previously unpopulated Venetian islands for a whole month just to be sure?

Whatever the "market" -- no matter what harm it may do -- there is someone, somewhere who (whether for cold, hard money, or some other poor reason) is willing to supply it.

Fortunately, easily-forgeable vaccination cards are not considered proof of vaccination for a holiday. Only a governmentally-dispensed certificate or the app is.

Hopefully it will be enough to charge these immoral players with fraud.
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Laka Strolistandiler
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Postby Laka Strolistandiler » Wed Jun 02, 2021 1:14 am

I’m probably going to get a shot of Chumakov’s CoviVak this or next week, wish me good luck fellas...
||||||||||||||||||||
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-SARS-
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Postby -SARS- » Wed Jun 02, 2021 1:16 am

It's amazing that people will go to so much work to fake being vaccinated when it would be easier to just get the vaccine.

I never knew there were so many people concerned about protecting viruses' right to procreate. Gives me faith in humanity. :lol:
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The Free Joy State
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Postby The Free Joy State » Wed Jun 02, 2021 1:20 am

Austria-Bohemia-Hungary wrote:
The Free Joy State wrote:Whatever the "market" -- no matter what harm it may do -- there is someone, somewhere who (whether for cold, hard money, or some other poor reason) is willing to supply it.

Fortunately, easily-forgeable vaccination cards are not considered proof of vaccination for a holiday. Only a governmentally-dispensed certificate or the app is.

Hopefully it will be enough to charge these immoral players with fraud.

In America, such bad actors were also charged with identity theft (which would seem necessary if someone's real documents were used as a basis for the faked records), forging government documents, and falsifying medical records.
Last edited by The Free Joy State on Wed Jun 02, 2021 1:21 am, edited 1 time in total.
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Laka Strolistandiler
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Postby Laka Strolistandiler » Wed Jun 02, 2021 1:24 am

The Free Joy State wrote:
Austria-Bohemia-Hungary wrote:Hopefully it will be enough to charge these immoral players with fraud.

In America, such bad actors were also charged with identity theft (which would seem necessary if someone's real documents were used as a basis for the faked records), forging government documents, and falsifying medical records.

I wish Russians treated this matter with the same vigilance...
||||||||||||||||||||
I am not a Russian but a Cameroonian born in this POS.
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Austria-Bohemia-Hungary
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Postby Austria-Bohemia-Hungary » Wed Jun 02, 2021 1:25 am

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Blasted Craigs
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Been away, but thought this was worth sharing

Postby Blasted Craigs » Wed Jun 02, 2021 1:56 am

So, not misinformation since the CDC has stated that Chloroquine can be useful in treating COVID, but in 2005 the Journal of virology stated that Chloroquine was effective in treating and preventing the spread of coronovirus, hell, here is the quote from the artical.
Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
Severe acute respiratory syndrome (SARS) is an emerging disease that was first reported in Guangdong Province, China, in late 2002. The disease rapidly spread to at least 30 countries within months of its first appearance, and concerted worldwide efforts led to the identification of the etiological agent as SARS coronavirus (SARS-CoV), a novel member of the family Coronaviridae [1]. Complete genome sequencing of SARS-CoV [2, 3] confirmed that this pathogen is not closely related to any of the previously established coronavirus groups. Budding of the SARS-CoV occurs in the Golgi apparatus [4] and results in the incorporation of the envelope spike glycoprotein into the virion. The spike glycoprotein is a type I membrane protein that facilitates viral attachment to the cellular receptor and initiation of infection, and angiotensin-converting enzyme-2 (ACE2) has been identified as a functional cellular receptor of SARS-CoV [5]. We have recently shown that the processing of the spike protein was effected by furin-like convertases and that inhibition of this cleavage by a specific inhibitor abrogated cytopathicity and significantly reduced the virus titer of SARS-CoV

Link of the article from the website.

Now, the Journal of Virology is the official publication of the National Institute of Health, of which Dr. Fauci has been the director of since 1984.
Links.

Now, this means Dr Fauci should have been aware that Chloroquine was effective in treating the various forms of coronavirus. But, when Trump stated Chloroquine was an effective treatment in Jul of 2020, Dr. Fauci stated that, to quote the BBC article, "On Wednesday Dr Anthony Fauci, a leading member of the White House coronavirus task force, told the BBC that hydroxychloroquine was not effective against the virus."
Link to the BBC article.

Now, I havn't posted in a while, but I wonder, do you think Dr. Fauci was confused, or do you think maybe, just maybe, he shouldn't be hailed as the end all expert, and if not a simple mistake, why did he state and recommend it was dangerous to treat those dying from coronavirus with a cheap and effective treatment per the 2005 study that was done by Dr. Fauci's own organization he was a director of when the study was done? Remember, people died due to the lack of a treatment as the pharmaceutical companies were trying to create a vaccine for.....Not that CHloroquine would be a cure per sey, but it was an effective treatment that could have saved thousands of lives.

Just wondering what you all think about this, and since everything Covid related gets shoved into this thread, I'll just put it here. Remember, I am not debating whether the vaccine out are effective or not, but why Chloroquine was argued by Dr Fauci to be ineffective when he should have known it was an effective treatment.
Last edited by Blasted Craigs on Wed Jun 02, 2021 2:00 am, edited 2 times in total.
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The Huskar Social Union
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Postby The Huskar Social Union » Wed Jun 02, 2021 2:00 am

=07`
-SARS- wrote:It's amazing that people will go to so much work to fake being vaccinated when it would be easier to just get the vaccine.

I never knew there were so many people concerned about protecting viruses' right to procreate. Gives me faith in humanity. :lol:

Yeah getting the vaccine for me took the better part of an hour, like half of that was driving to and from the vaccination centre. The actual injection took like 15 seconds. Bam done, went and waited for 15 minutes then off to the rest of my day.

As for side effects mine lasted a day and that was it. Most people will experience them for a few days at most, maybe a week or two.
Last edited by The Huskar Social Union on Wed Jun 02, 2021 2:02 am, edited 1 time in total.
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CoraSpia
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Ex-Nation

Postby CoraSpia » Wed Jun 02, 2021 2:27 am

The Huskar Social Union wrote:=07`
-SARS- wrote:It's amazing that people will go to so much work to fake being vaccinated when it would be easier to just get the vaccine.

I never knew there were so many people concerned about protecting viruses' right to procreate. Gives me faith in humanity. :lol:

Yeah getting the vaccine for me took the better part of an hour, like half of that was driving to and from the vaccination centre. The actual injection took like 15 seconds. Bam done, went and waited for 15 minutes then off to the rest of my day.

As for side effects mine lasted a day and that was it. Most people will experience them for a few days at most, maybe a week or two.

The thing is, it doesn't matter if the reasons for refusing a vaccine make no sense. I did a lot of research before getting mine and found that...yeah, the reasons against made very little sense, however others have come to a different conclusion. We can think they're morons all we like, but it's still their right and their right alone to decide what goes into their bodies and what medical treatments they consent to. I'm all for encouraging people to get vaccinated in the way that some US states have done, but I draw the line at negative incentives.
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-SARS-
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Postby -SARS- » Wed Jun 02, 2021 2:32 am

Blasted Craigs wrote:So, not misinformation since the CDC has stated that Chloroquine can be useful in treating COVID, but in 2005 the Journal of virology stated that Chloroquine was effective in treating and preventing the spread of coronovirus, hell, here is the quote from the artical.
Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
Severe acute respiratory syndrome (SARS) is an emerging disease that was first reported in Guangdong Province, China, in late 2002. The disease rapidly spread to at least 30 countries within months of its first appearance, and concerted worldwide efforts led to the identification of the etiological agent as SARS coronavirus (SARS-CoV), a novel member of the family Coronaviridae [1]. Complete genome sequencing of SARS-CoV [2, 3] confirmed that this pathogen is not closely related to any of the previously established coronavirus groups. Budding of the SARS-CoV occurs in the Golgi apparatus [4] and results in the incorporation of the envelope spike glycoprotein into the virion. The spike glycoprotein is a type I membrane protein that facilitates viral attachment to the cellular receptor and initiation of infection, and angiotensin-converting enzyme-2 (ACE2) has been identified as a functional cellular receptor of SARS-CoV [5]. We have recently shown that the processing of the spike protein was effected by furin-like convertases and that inhibition of this cleavage by a specific inhibitor abrogated cytopathicity and significantly reduced the virus titer of SARS-CoV

Link of the article from the website.

Now, the Journal of Virology is the official publication of the National Institute of Health, of which Dr. Fauci has been the director of since 1984.
Links.

Now, this means Dr Fauci should have been aware that Chloroquine was effective in treating the various forms of coronavirus. But, when Trump stated Chloroquine was an effective treatment in Jul of 2020, Dr. Fauci stated that, to quote the BBC article, "On Wednesday Dr Anthony Fauci, a leading member of the White House coronavirus task force, told the BBC that hydroxychloroquine was not effective against the virus."
Link to the BBC article.

Now, I havn't posted in a while, but I wonder, do you think Dr. Fauci was confused, or do you think maybe, just maybe, he shouldn't be hailed as the end all expert, and if not a simple mistake, why did he state and recommend it was dangerous to treat those dying from coronavirus with a cheap and effective treatment per the 2005 study that was done by Dr. Fauci's own organization he was a director of when the study was done? Remember, people died due to the lack of a treatment as the pharmaceutical companies were trying to create a vaccine for.....Not that CHloroquine would be a cure per sey, but it was an effective treatment that could have saved thousands of lives.

Just wondering what you all think about this, and since everything Covid related gets shoved into this thread, I'll just put it here. Remember, I am not debating whether the vaccine out are effective or not, but why Chloroquine was argued by Dr Fauci to be ineffective when he should have known it was an effective treatment.


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Picairn
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Postby Picairn » Wed Jun 02, 2021 2:58 am

Blasted Craigs wrote:-snip-

Several points here.

1. The study was tested on animal cells, not humans, in a lab setting. Specifically:
Results: We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells.

On page 9 the article's methodology reveals:
Vero E6 cells (an African green monkey kidney cell line) were infected with SARS-CoV (Urbani strain) at a multiplicity of infection of 0.5 for 1 h. The cells were washed with PBS and then incubated in OPTI-MEM (Invitrogen) medium with or without various concentrations of either chloroquine or NH4Cl (both from Sigma). Immunofluorescence staining was performed with SARS-CoV-specific hyperimmune mouse ascitic fluid (HMAF) [8] followed by anti-mouse fluorescein-coupled antibody.

Humans, as we know, are different from animals. What is successful on animal cells may be different from human cells, which is why there are different testing periods for animals and humans (clinical trials).

The authors do suggest that their positive results in primate cell culture are promising (see page 9) and the use of chloroquine for the clinical management of SARS is presented as a possibility. Nonetheless, that is irrelevant, because...

2. This article only studied the effects of chloroquine on SARS-CoV coronavirus, the virus that caused the 2002–2004 SARS outbreak. Note its date, 2005. The SARS-CoV-2, the virus that is ravaging the world right now, is its successor with substantial differences, most notably the furin-like cleavage site in its S proteins, absent in the S proteins of the original SARS-CoV.

3. With the differences in mind, we can not claim that chloroquine would work for SAR-CoV-2 the same as SARS-CoV-1. The former was not identified until the 2019 outbreak in Wuhan.

4. We should also learn the differences between chloroquine and hydroxychloroquine. https://emedicine.medscape.com/article/1229016-overview
Chloroquine and hydroxychloroquine belong to the quinolone family. Although their therapeutic and toxic doses differ, they are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity.


5. Now, there are several meta-analyses on the effectiveness of these two drugs against Covid-19 in patients.

  • Lewis K, Chaudhuri D, Alshamsi F, Carayannopoulos L, Dearness K, Chagla Z, et al. (2021) The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis: A systematic review and meta-analysis of randomized trials. PLoS ONE 16(1): e0244778. https://doi.org/10.1371/journal.pone.0244778
This article says "the current body of evidence failed to show clinical benefit for prophylactic hydroxychloroquine and showed a higher risk of adverse events when compared to placebo or no prophylaxis."

  • Ghazy, R.M., Almaghraby, A., Shaaban, R. et al. A systematic review and meta-analysis on chloroquine and hydroxychloroquine as monotherapy or combined with azithromycin in COVID-19 treatment. Sci Rep 10, 22139 (2020). https://doi.org/10.1038/s41598-020-77748-x
This article concludes:
Treating COVID-19 patients with CQ/HCQ did not decrease mortality. even it was increased if AZM was added. Besides, CQ/HCQ alone or in combination with AZM increased the duration of hospital stay. Overall virological cure rate and that on days 4, 10, or 14 were not affected by receiving HCQ. Adding AZM to HCQ/CQ did not show any benefit in terms of virological cure as well. Te Need for MV was not improved by exposure to CQ/HCQ alone or in combination with AZM. Moreover, CQ/HCQ, did not neither shorten the duration till conversion to negative PCR, prevent radiological progression, nor affect clinical worsening of the disease. Future randomized clinical trials are needed to confirm these conclusions.

  • Axfors, C., Schmitt, A.M., Janiaud, P. et al. Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials. Nat Commun 12, 2349 (2021). https://doi.org/10.1038/s41467-021-22446-z
This one tells us:
This collaborative meta-analysis of 28 published or unpublished RCTs, including 10,319 patients, shows that treatment with HCQ was associated with increased mortality in COVID-19 patients, and there was no benefit from treatment with CQ.

  • Zakariya Kashour, Muhammad Riaz, Musa A Garbati, Oweida AlDosary, Haytham Tlayjeh, Dana Gerberi, M Hassan Murad, M Rizwan Sohail, Tarek Kashour, Imad M Tleyjeh, Efficacy of chloroquine or hydroxychloroquine in COVID-19 patients: a systematic review and meta-analysis, Journal of Antimicrobial Chemotherapy, Volume 76, Issue 1, January 2021, Pages 30–42, https://doi.org/10.1093/jac/dkaa403
Another one:
Moderate certainty evidence suggests that HCQ, with or without azithromycin, lacks efficacy in reducing short-term mortality in patients hospitalized with COVID-19 or risk of hospitalization in outpatients with COVID-19.

I encourage you to review the latest meta-analyses of the data.

TL;DR: If you prefer a short debunk, see this Reuters factcheck: https://www.reuters.com/article/uk-fact ... SKCN2512A7
Last edited by Picairn on Wed Jun 02, 2021 3:00 am, edited 2 times in total.
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Dakini
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Postby Dakini » Wed Jun 02, 2021 2:58 am

The Black Forrest wrote:Well now. A deputy in Denver developed an attitude over the vaccine. To the point where he would antagonize people over it.

Welp….he got covid and died two weeks later.


https://moguldom.com/355383/maga-police ... -of-covid/

I heard about that.

Though really, he shouldn't have been a deputy at the time of his death since he should have been fired after beating an inmate with nunchaku.

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Postby Page » Wed Jun 02, 2021 3:15 am

Dakini wrote:
The Black Forrest wrote:Well now. A deputy in Denver developed an attitude over the vaccine. To the point where he would antagonize people over it.

Welp….he got covid and died two weeks later.


https://moguldom.com/355383/maga-police ... -of-covid/

I heard about that.

Though really, he shouldn't have been a deputy at the time of his death since he should have been fired after beating an inmate with nunchaku.


He protecc

He attacc

But most of all he should have complied with the virus, he wouldn't have died if his immune system wasn't resisting. Also, are we sure it wasn't really a fentanyl overdose?
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Postby Dylar » Wed Jun 02, 2021 4:49 am

Kowani wrote:
Galloism wrote:Still nothing for me in Florida.

DeSantis says never

Indiana isn't doing it either
Although, I do think that Holcomb makes some good points as to why he doesn't want to do that
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Postby Ifreann » Wed Jun 02, 2021 5:37 am

Kowani wrote:West Virginia to give away guns as Covid-19 vaccine incentive

The state will give away five custom hunting rifles and five custom shotguns through its lottery, with the drawings taking place on June 20 for Fathers Day.

There will be a series of lottery drawings taking place weekly from June 20 through August 4, for which any West Virginian who’s received at least one dose of the Covid-19 vaccine will be eligible to register. The lottery will also give one resident $1 million—as other states have done—along with prizes like full-ride scholarships, custom trucks and lifetime hunting and fishing licenses.

In addition to its lottery, West Virginia is also giving away $100 in savings bonds or gift cards to everyone ages 16-35 in the state who is fully vaccinated.

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Postby The Huskar Social Union » Wed Jun 02, 2021 6:17 am

Kowani wrote:West Virginia to give away guns as Covid-19 vaccine incentive

The state will give away five custom hunting rifles and five custom shotguns through its lottery, with the drawings taking place on June 20 for Fathers Day.

There will be a series of lottery drawings taking place weekly from June 20 through August 4, for which any West Virginian who’s received at least one dose of the Covid-19 vaccine will be eligible to register. The lottery will also give one resident $1 million—as other states have done—along with prizes like full-ride scholarships, custom trucks and lifetime hunting and fishing licenses.

In addition to its lottery, West Virginia is also giving away $100 in savings bonds or gift cards to everyone ages 16-35 in the state who is fully vaccinated.

Course they would

I mean why wouldnt they
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