The life of an individual human is measly and insignificant. One of quadrillions of sorrowed souls, the vast majority live a life on unending despair and poverty. The God-Emperor, in his dream of an enlightened and united humanity, now sits as a living corpse, unable to weep for the horror he created. Instead of a humanity capable of collectively saving each other; they now exist as amass horde of ignorant savages, clinging to the notions of faith as the one and only savior. For no matter the pain, no matter the hardship, the will and emotion of mankind is all that can save them from the noose.
Within Skarth, in the Hive City of Aslog, plumes of toxic chemicals spew into the atmosphere. At the origin of these plumes, little better than slaves, work untold millions of laborers. There lives short and forgetful, most will be condemned to a life of ignominy, little more than a statistic a local lord concerns himself with for but a moment. For it is the xeno, the mutant, and the heretic that preoccupy the Imperium; the Emperor's dream now lay long forgotten, and the benefits of slavery tip the scale of utilitarian concern. The Imperium, despite the propoganda, exists as a testament, perhaps more than Chaos, to the cold truth of the galaxy; humans live, suffer, and die. For every hero, for every genius and famed warrior, millions die alone and forgotten, their deeds known only to them, and lost with them as well.
Within these self-sacrificing hordes, the seeds of doubt, hate, and jealousy are planted. Tzeentch, king of mutants and architect of fate, offers his followers advancement of their station, and respite for the long-pressed mutants, whom suffer the penalties of the Imperium without the false hope of salvation. Nurgle, the God of decay, carries with him the one immutable truth; that these poor souls will never leave their homes, and that only through acceptance shall they glean happiness and meaning from their pitiful existence. Slaanesh, the Dark Prince of excess, offers escape through sensation and pleasure, proving effective in allowing the ignorance of real life suffering. Khornate followers strike against the injustice and inequality of the world; they reject its premise, and seek to damage and destroy the world they were saddled with, glorifying this pure process of destruction, the destruction of an unjust, despotic regime, and unjust, despotic reality.
Despite these agents of change, some still cling to the hopes and dreams the God-Emperor gave his children. No matter the pointlessness, no matter the darkness, these loyalists fight for their common man; they fight for the dream, be it real or imaginary, of a united and prosperous humanity, of the future long lost, and for the God-Emperor who still watches over them with pride, constantly fighting to save his children. It is these men and women that keep the Imperium running, that keep it from dying the death long forseen by the followers of Chaos.
Within the Hive, the residents stir. Production quotas were up. The 23rd Remembrance Day of the God-Emperor was no longer a work-free holiday. Discontent was rising, and with the news of the 13th Black Crusade being spread by merchants and Imperial Guardsmen on their way to combat it, many were fearful of what may happen should the warriors of Chaos break free from the Eye. News of cults in the Underhive and armies of mutants spread throughout the Hive; and members of the PDF were sent to investigate,a and report back to the Inquisition.
Now, a a regiment of PDF and government enforcers were pushing through the Underhive, slowly, exterminating mutants too weak to flee. This ancient and forgotten district held many secrets, and even more treasures. Those brave enough to explore, and tough enough to survive, could gain much.
Meanwhile, the Black Ships and missed their mark. The Black Crusade had called forth all available armies and ships, leaving fewer and fewer with the option of tithing. Psykers, possessing a latent connection to the Warp, began feeling strange, as the barrier between the Materium and Chaos slowly faded. Daemons and spirits began prodding at the weaker of minds, offering promises and guarantees, or sometimes outright possessing. The Hive was on the brink, as was all of Skarth, and those with psychic ability had much to both win and lose.